Posted in 4-MEC on June 20th, 2011
4-MEC is a designer drug legally available in the market. The research chemical must only be bought from reliable sources. It can be consumed in pellet, crystal or powder form. It can be ingested nasally or orally.
4-MEC is a research chemical that acts as a stimulant. It is widely available. There are two ways of obtaining the chemical, legal and illegal. It is highly dangerous to obtain it through illegal sources as they may have tampered with the research chemical to produce dangerous results.
While most vendors online may offer lucrative deals like cheaper prices and more quantities, it is highly risky to believe any of them as they may be adding cheaper substances to the chemical thus making it especially dangerous for consumption. The best thing to do is to identify a trust worthy site. Most chemicals have their own website. This makes them very useful. Unfortunately 4-MEC does not. However, trustworthy vendors do stock these chemicals and are a good place to start your search. Other trustworthy sources are online websites that have governmental approvals on them.
Like all businesses these vendors too are referred from past customers. So if you know anyone who uses these research chemicals, be sure to ask him/her where he/she sources it from. Some people test the chemicals they receive in the lab before using them. This is also a good idea if you have access to these labs. 4-MEC gives the best results when up to 100 gms is eaten rather than sniffed. The research chemical can create an urge to redose during the comedown and must thus be taken sensibly.
It does not have any bad effects, just a little bit of sweatiness. On consuming 4-MEC one experiences euphoria, relaxation, clear headedness, stimulation, etc. The effects last anywhere from 20 minutes to 3-4 hours. It does not have a particularly nasty comedown and is generally considered user friendly and mild. It is often considered a good replacement for mephedrone. It is reported to be an inactive intranasal. Many people suggest using it as a party drug as it stimulates people and helps them loosen up. There are claims that the drug causes no hangover the next day.
It is available in powder, crystal and pellet forms. It is touted as a great choice for clubbers. It also creates sexual stimulation and a general feeling of happiness. The effect of the drug is definitely very similar to that of mephedrone. This party drug can be great provided it is taken in the right dose and by responsible adults. Any overdose can have severe effects on the health of an individual. Be sure to buy 4-MEC from a reliable source only.
Posted in JWH on June 20th, 2011
JWH-18 is the main component in synthetic cannabis. It exists in various research chemicals or party drugs. It is commonly found as a part of Spice. It is sold legally in the United Kingdom.
JWH-18 is a legal narcotic sold in the United Kingdom, primarily for research purposes. It is one of the many analogues discovered by the organic chemist John W Huffman. JWH-18 exhibits properties that exist in cannabis. This is possibly what makes it such a popular designer drug.
JWH-18 is found to influence the CH1 and CH2 receptors in a major way. This is what makes it so popular among users. It is found that the drug can be taken either nasally or orally. It is found to be used to create a feeling of euphoria in the user. What separates JWH-18 from other cannabinoids is that it is created by altering the chemical composition of naturally occurring marijuana. It is sold in a white solid form. The degradation process often leads to it changing its appearance to a yellow brown, gummy appearance. When the substance is found in this color it means the substance has been subjected to oxidization and is thus not completely pure.
In terms of safety, while there have been reports of adverse effects like psychological dependence, it is observed that these were usually the result of overuse. If used in the right quantities and by responsible individuals, JWH-18 should not create any sort of long term adverse effect. As part of his study, a writer named Kevin Keck has observed that the drug is in fact safe for use, provided once again; it is consumed in the right quantities and responsibly. It enjoys a legal status in many countries including the United Kingdom, Unites States of America, etc.
The chemical displays a typical tachyphylactic response to repeated dosing. Its effects become lesser as a result of repeated dosing and the duration also reduces considerably. It is most commonly sold in incense form and is smoked to achieve the high. It is commonly found in variants of spice and is in fact the chief ingredient of the same. Researchers have found that JWH-18 is four times more addictive that the standard THC that exists in natural cannabis. The chemical is found to be much stronger than its other variants like JWH-250.
JWH-18 is much harder to detect in the human body than natural cannabis. It can only be detected by performing specific tests on a subject’s urine sample. The effect most users feel is visual distortions, a higher buzz than marijuana and lethargy. Once again it is recommended that JWH-18 to be used only in small doses due to its high potency.
Posted in JWH on June 20th, 2011
JWH-122 is a legal narcotic. It is essentially a synthetic cannabinoid created to mimic the effect of cannabis by displaying its affinity for CB1 and CB2 receptors. It is considered stronger than JWH-250 yet lighter than JWH-018.
JWH-122 is a legal narcotic that is available to people interested in experimenting with research chemicals. A research chemical also known as a designer drug is a naturally occurring narcotic whose chemical properties have been altered to make it safe. JWH-122 is a synthetic cannabinoid. The company that manufactures it claims that its chemical formula is C26H27NO with a molecular mass of 369.498g/mol. JWH-122 is another offering in a series of cannabinoids developed by John W Huffman. Users report that its potency is quite high and much more than its more popular form JWH-250.
JWH-122 is an analgesic chemical from the naphthoylindole family. The chemical is quite popular among young experimenters. Many of them prefer to ingest it orally. It has the same effect as a cannabinoid. Its effectiveness has something to do with the fact that it shows strong affinity for the CB1 & CB2 receptors. This research chemical is extremely popular as it provides the same effect as cannabis but is considered legal and less dangerous. People normally choose to ingest around 1-2 grams of the drug.
So far, few people have complained of any dangerous side-effects from the drug. It has been researched by various government bodies and has been approved as safe for research. These research chemicals are available in plenty of vendor websites. Anyone interested in actually purchasing the cannabinoid must make sure that he or she has selected an authentic source which has not added anything to the chemical. This is possible and has been known to happen in the past. Despite its status as a safe research chemical, it must be noted that unless taken in the right doses it can cause harmful side effects.
Many regular cannabinoid experimenters find this research chemical preferable as its effects are more manageable and have less of a negative effect. However again, people who have increased the dose have suffered. The effect of this cannabinoid is similar to other cannabinoids; a user experiences euphoria and finds his senses enhanced. It is taken for recreational purposes and the user often experiences the high for 3-4 hours. While JWH-122 is considered stronger than other popular versions like JWH-210 it is considered less potent than JWH-018. This is considered to be a good thing by many who say that they have experienced paranoia and other such strong symptoms from the other versions. JWH-122 is considered legal in the United Kingdom and USA. It is normally sold to people interested in performing JWH-122 research.
Posted in JWH on June 20th, 2011
JWH is an analgesic chemical which belongs to the naphthoylindole family and functions as a full agonist at those of the CB1 and CB2 cannabinoid receptors. JWH is administered to rats and this result in the excretion of the indole-N-desalkyl metabolite along with several other hydroxylated metabolites. The highest signals could be observed for hydroxylated N-desalkyl metabolites. First synthesized by Dr. John W. Huffman it was found in the herbal smoking blends like that of Spice. Compared to THC JWH is far more intense and so are its effects which when compared to smoking cannabis shows it’s nature.
JWH is primarily synthesized for radioligand binding purposes. JWH shows a traditional tachyphylactic response in case of repeated dosing, along with a notable decrease in the effect and duration after about 3 days of chronic nature dosing. JWH is believed to inhibit enzymes like CYP1A2, CYP2C9, CYP2C19 and CYP3A4.
Though it is based on the structure of WIN 55,212-2, JWH believes in analogizing lack of a methyl group at C-2. When it comes to the metabolism of this compound, its accumulation in peripheral tissues was shown after about 7 days of chronic dosing. This shows that the drug undergoes metabolism and elimination phases. The half life of this drug is about two hours (112.2min).
JWH does not bind the hERG, the human gene encoding that is required for cardiovascular potassium channels. Therefore it hardly creates an increased QT interval that may have deleterious and even deadly effects on cardiovascular system. When tested at the highest laboratory dose some respiratory depression was noticeable that resulted in the death of some animals. However the deaths were caused by catatonia and respiratory depression, because organ toxicity of any type was not detected.
JWH does not really interfere with the DNA in vivo. The combustion products of this material are not and they are not tested for the carcinogenic properties, rather the P.O. administration did not result in genotoxicity
Male rats have shown greater sensitivity to JWH than the female counterparts. This often resulted in increased sensitivity in the male humans when compared to females, although abnormalities in the CB1/CB2 receptor distribution in both male and female rats have been seen in previous studies. So if you are in demand of this drug or wish to purchase it for some purpose, do remember to learn all relevant details pertaining to it for the best results.
Posted in research chemicals for sale on June 20th, 2011
The trick to finding genuine research chemicals for sale is to look for trusted online sellers. Many websites try to pull scams to cheat people out of their money.
Finding research chemicals for sale might be easy on the internet, but knowing the product is pure and genuine will prove more difficult. The sale of research chemicals is steadily growing, and as many of them are now available legally, the number of online vendors is also on the rise. Despite the controversy surrounding these drugs, most customers are still keen on buying because they are safe to use and legally available. So, what do keep in mind when trying to buy research chemicals for sale? Well, the most important factor is the trustworthiness of the vendor.
With the rapidly growing number of online sites advertising research chemicals there are sure to be some scammers and fraudster who are looking to make some easy money. You need to be on the lookout for scam sites that will take your money and will not deliver the products. There are also websites that will tell you that they are selling a particular research chemical, but they will deliver a different drug that may have potentially harmful side effects. Some websites sell the genuine products when they have they supply, but when they run out they switch back to selling mislabeled potentially toxic products that they try to pass off as the real thing. You need to on guard for all these things to prevent yourself from purchasing a dangerous drug.
There are a few ways you can safeguard your money and ensure that a website has genuine research chemicals for sale. Trust the recommendations of your friends, but be wary of suggestions on online forums, unless it is substantiated by other forum members. Make sure that the website you are buying from is professional looking with a user-friendly interface because scam websites often don’t pay attention to these details. Don’t trust sites that offer drugs that available nowhere else and make sure that the sale comes with a set of terms and conditions.
When you are looking for research chemicals for sale try to find websites that offer safe encrypted payment modes. Your credit card details are important information that you should be wary of giving out to just about anyone. Often the best way to find out whether a site is selling you the genuine product is to order a small sample. If you find that the drug is satisfactory and seems genuine then you can order a bigger shipment.